Stephens 19. Name these genetic disorders, for ten points each.
1. (10) Mutation of the HEXA gene results in this fatal disease, in which harmful quantities of ganglioside GM2 accumulate in the nerve cells of the brain.
Answer: Tay-Sachs disease
2. (10) Symptoms include a webbed neck, low hairline, and abnormal bone development. An absence of a second sex chromosome in addition to the single X causes this disease.