Not nsaid Action: analgesic(pain reliever), antipyretic



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Acetaminophen (Tylenol)
Max Dose?

Class: Analgesic, not nsaid

Action: analgesic(pain reliever), antipyretic(fever reducer)

Adverse reactions/side effects: HEPATIC FAILURE, HEPATOTOXICITY (OVERDOSE). Overdose because of one metabolic pathway is over utilized & a minor one is used to a greater extent accumulating in Liver

Dose: PO (Adults and Children > 12 yr): 650 mg q 4-6 hr

Max = 4000mg/24 hrs





Aspirin (ASA)


Class: NSAID

Action: analgesia, reduces inflammation, reduces fever, and affects blood clotting

Adverse reactions/side effects: GI BLEEDING, dyspepsia, epigastric distress, nausea EXFOLIATIVE DERMATITIS, STEVENS-JOHNSON SYNDROME, TOXIC EPIDERMAL NECROLYSIS. ALLERGIC REACTIONS INCLUDING ANAPHYLAXIS AND LARYNGEAL EDEMA.

Dose: PO (Adults): 650mg 4-6q daily






Celecoxib (Celebrex)


Class: NSAID (selective)

Action: inhibits COX-2 pain relief and inflamation

Adverse reactions/side effects: GI BLEEDING, EXFOLIATIVE DERMATITIS, STEVENS-JOHNSON SYNDROME, TOXIC EPIDERMAL NECROLYSIS,

Dose: PO 100-200(RA)






Ibuprofen (Motrin)


Class: NSAID

Action: analgesic, anti-inflammatory, antipyretic

Adverse reactions/side effects: GI BLEEDING, HEPATITIS, constipation, dyspepsia, nausea, vomiting, EXFOLIATIVE DERMATITIS, STEVENS-JOHNSON SYNDROME, TOXIC EPIDERMAL NECROLYSIS, ALLERGIC REACTIONS INCLUDING ANAPHYLAXIS

Dose: PO (Adults): Anti-inflammatory--300-800 mg 3-4 times daily (not to exceed 3600 mg/day).






Ketorolac (Toradol)


Class; Non-Opioid NSAID – prescription

Action: moderate – severe pain 5 DAYS OR LESS

Adverse reactions/side effects: : GI BLEEDING, EXFOLIATEVE DERMATITIS, STEVENS-JOHNSON SYNDROME, TOXIC EPIDERMAL NECROLYSIS, drowsiness, anaphylaxis

Dose: IM/ IV 15-30 mg q6h, PO 10 mg q4-6 h






Tylenol with Codeine (#3 and #4)


Class: Narcotic NSAID Pain reliever.

Action: mild – moderate pain. metabolizes to morphine

Adverse reactions/side effects: Constipation

Dose: PO 15-60 mg q4-6hr


Notes: Step II drug. #3 (30 mg) #4 (60 mg Codeine)





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