When an example is made of the son of Maryam (‘Isa) your people laugh uproariously. They retort, "Who is better then, our gods or him?" They only say this to you for argument's sake. They are indeed a disputatious people.
He is only a slave on whom We bestowed Our blessing and whom We made an example for the tribe of Israel.
If We wished, We could appoint angels in exchange for you to succeed you on the earth. (Surat az-Zukhruf: 57-60)
Just after these verses, Allah declares that Jesus (as) is a sign of the Day of Judgement.
He is a Sign of the Hour. Have no doubt about it. But follow me. This is a straight path. (Surat az-Zukhruf: 61)
Ibn Juzayy says that the first meaning of this verse is that Jesus (as) is a sign or a precondition of the Last Hour. We can say that this verse is a clear indication that Jesus (as) will come back to earth at the end times. That is because Jesus (as) lived six centuries before the revelation of the Qur'an. Consequently, we cannot interpret his first coming as a sign of the Day of Judgement. What this verse actually indicates is that Jesus (as) will come back to earth towards the end of time, that is to say, during the last period of time before the Day of Judgement and this will be a sign for the Day of Judgement. Allah surely knows the best.
The Arabic of the verse "He is a Sign of the Hour" is "Innahu la ‘ilmun li’s-sa’ati…" Some people interpret the pronoun "hu" (he) in this verse as the Qur'an. However, the preceding verses explicitly indicate that Jesus (as) is mentioned in the verse: "He is only a slave on whom We bestowed Our blessing and whom We made an example for the tribe of Israel"3
In Sahih Muslim, it is also stated that the ahadith in which it is said that the Prophet Jesus (as) will descend amongst people at the end of time have reached the degree of being mutawatir, i.e. narrated by so many people in each generation that it is not possible to have any doubt of their authenticity, and that it is counted as one of the major signs of the Day of Rising. (Sahih Muslim, 2/58)
Hudhayfah ibn Usayd al-Ghifari said, "The Messenger of Allah (saas) came to us all of a sudden as we were (busy in a discussion). He said: ‘What are you discussing?’ We said: ‘We are discussing the Last Hour.’ Thereupon he said: ‘It will not come until you see ten signs before it’ - and (in this connection) he made mention of the smoke, the Dajjal, the beast, the rising of the sun from the west, the descent of ‘Isa the son of Maryam (as), Yajuj and Majuj, and landslides in three places, one in the east, one in the west and one in Arabia at the end of which fire will burn forth from the Yemen, and drive people to the place of their assembly." (Sahih Muslim) (4)
Another verse indicating the second coming of the Jesus (as) is the following;
When the angels said, "Maryam, your Lord gives you good news of a Word from Him. His name is the Messiah, ‘Isa, son of Maryam of high esteem in this world and the hereafter, and one of those brought near. He will speak to people in the cradle, and also when fully grown, and will be one of the righteous," she said, "My Lord! How can I have a son when no man has ever touched me?"