Health Consultation Assessment of Drinking Water Quality And Cancer Incidence Scituate, ma



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e. Liver Cancer

In the town of Scituate as a whole, liver cancer occurred less often than expected for the time period 1987-1997 (two cases observed versus about four cases expected). Both cases of liver



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cancer occurred in CT 5051.02, located in the southwestern portion of the town. Approximately one case of liver cancer was expected to occur during the time period evaluated in CT 5051.02. No cases of liver cancer occurred in CT 5052, the location of the Third Cliff Area.



1) Gender Distribution

Liver cancer is most commonly diagnosed among males in the United States (El-Serag et al


1999). Both individuals who were diagnosed with liver cancer between 1987 and 1997 in
Scituate were male.

2) Age Distribution

The risk for developing liver cancer increases with age with most cases of this cancer being diagnosed in individuals over age 55 (London and McGlynn 1996). Both individuals diagnosed with liver cancer in Scituate during the time period evaluated were over age 55 at the time of diagnosis.



3) Occupation

Vinyl chloride is a known human carcinogen and occupational exposure to this chemical


(e.g., via PVC manufacturing) has been associated with the development of liver cancer

(London and McGlynn 1996). Unfortunately, occupational information available through the MCR for the individuals diagnosed with liver cancer in Scituate was not complete. Therefore, the role that occupation may have played in the development of liver cancer in these individuals in unclear.






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