I think Jude and Genesis both make it very clear that there was no human male intermediary in these cases but rather direct angelic contact (such will be the case in antichrist's pseudo-"virgin-birth" as well). See the link: Satan's antediluvian attack on the purity of the human line (the Nephilim).
As to Ephesians 2:2, I explain it this way in SR #1 (see the link):
"the ruler whose realm of authority is the atmosphere" (Greek aer, referring to the first heaven and thus stressing Satan's temporary, limited authority over the earth), [means that the devil] does not remain here at all times, but on specified occasions assembles with the other angels in the presence of God, the third heaven (Job 1:6; 2:1; and cf. 1Kng.22:19)."
See also in BB 2A: "The limits of Satan's control over the earth".
That is to say, the title shows the devil's realm is limited in control as far as the earth is concerned since he and his are unable to physically occupy it in the way human beings can, and this frustration on his part and the part of his followers explains much about the origin of his rebellion (see the link: "Satan's Revolutionary Platform").