Federalist Papers The Declaration of Independence relies on natural rights for its justification.
Slavery was a key point of argument throughout all stages of the creation of American government. The Constitution included many protections for slaveholders that ensured slavery would emerge from the Revolutionary Era in a stronger position than prior to it.
Popular concerns over the dangers of powerful central governments led to the adoption of the Articles of Confederation, which gave most power to the states.
The Articles proved ineffective because the central government lacked necessary powers (ability to tax, raise an army, etc.). This led many people to call for a new government.
The Constitution is a product of compromise (House and Senate, powers of the president, 3/5 compromise) that reflect tensions in American society.
The Constitution increased the power of the federal government relative to the states. This expansion caused many to worry about individual rights, which led to the ratification of the Bill of Rights.
The Bill of Rights protected many individual rights from infringement by the federal (not state) government. Many of these rights built on natural rights recognized in the Declaration.