Anthrax Vaccine: What You Need to Know

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Vaccine Information Statement

Anthrax Vaccine: What You Need to Know

Many Vaccine Information Statements are available in Spanish and other languages. See

Hojas de información sobre vacunas están disponibles en español y en muchos otros idiomas. Visite

1. Why get vaccinated?

Anthrax vaccine can prevent anthrax.
People can get anthrax disease from contact with infected animals or contaminated animal products such as wool, meat, or hides. The anthrax bacteria could also be used as a biological weapon.
Anthrax is not spread from person to person. It is spread in one of four ways, and signs and symptoms can vary depending on how anthrax enters the body:

  • Through breaks in the skin. Cutaneous anthrax causes blisters or bumps on the skin, swelling around the sore, and a painless skin sore (ulcer) with a black center. The sore is usually on the face, neck, arms, or hands.

  • From eating infected meat. Ingestion anthrax can cause fever and chills. It can affect the upper part of the gastrointestinal (GI) tract, the lower part of the GI tract, or both. When it affects the upper part, there is swelling of the neck or neck glands, sore throat, and painful swallowing or difficulty breathing. When it affects the lower GI tract, nausea and vomiting, stomach pain and swelling, and diarrhea may be present. The patient may also look flushed (red), have red eyes, or faint.

  • From inhaling spores of the bacteria that causes anthrax. Inhalation anthrax can cause shortness of breath, cough, chest discomfort, confusion, nausea or vomiting, stomachache, sweats, and dizziness.

  • From injecting heroin. Injection anthrax can result in swelling at the injection site, nausea and vomiting, and sweats.

All types of anthrax can cause fever, chills, fatigue, and headache. Anthrax can spread throughout the body and cause severe illness, including brain infections and even death, if left untreated.

2. Anthrax vaccine

Anthrax vaccine is approved by the Food and Drug Administration (FDA) and recommended for adults 18 through 65 years of age who are at risk of exposure to anthrax bacteria, including:

  • Certain laboratory workers who work with Bacillus anthracis

  • People who handle potentially infected animals or their carcasses

  • Some military personnel (determined by the Department of Defense)

  • Some emergency and other responders whose response activities might lead to exposure

These people should get 3 doses of anthrax vaccine, followed by booster doses for ongoing protection.
Anthrax vaccine is also recommended for unvaccinated people of all ages who have been exposed to anthrax. These people should get 3 doses of anthrax vaccine together with recommended antibiotic drugs.
Anthrax vaccine has not been studied or used in children less than 18 years of age. Because its use in exposed children is not approved by FDA, it must be used under an expanded access Investigational New Drug (IND) program and requires informed consent from a parent or legal guardian.

3. Talk with your health care provider

Tell your vaccine provider if the person getting the vaccine:

  • Has had an allergic reaction after a previous dose of anthrax vaccine, or has any severe, life-threatening allergies.

  • Is pregnant or thinks she might be pregnant.

  • Has a weakened immune system.

  • Has a history of anthrax disease.

In some cases, your health care provider may decide to postpone anthrax vaccination to a future visit.

People with minor illnesses, such as a cold, may be vaccinated. People who are moderately or severely ill should usually wait until they recover before getting anthrax vaccine.

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