Anderson, S. 1998. Hazard Analysis: Preparing for Natural Disasters, Lab Animal; 27(1):24-29.
Federal Emergency Management Agency (FEMA) Web site: http://www.fema.gov/.
"Animal in Disaster" a two module training program by FEMA.
Vogelweid, C. M. Developing emergency management plans for university laboratory animal programs and facilities. Contemporary Topics on Laboratory Animal Science 37(5):52-56.
Resources for Crisis Management in Zoos and other Animal Care Facilities. 1999.Published by the American Association of Zoo Keepers. Editors: Chan S. D., W. K. Baker, and D.L. Guerrero. Topeka, Kansas.
Heath, S. E. 1999. Animal Management in Disaster.Mosby Year Book. St Louis, MO.
The IACUC is responsible for overseeing and evaluating all aspects of animal care and use, and is charged with reviewing proposals* that involve animals to ensure that the criteria established in the PHSPolicy and the Animal Welfare Regulations (AWRs) are implemented. In its review of pro-posals, the Committee's primary goal should be to facilitate compliance with applicable laws, regulations and policies consistent with the performance of appropriate and productive scientific endeavors.
Protocol Review Criteria
Table A lists each review criterion of the PHSPolicy and AWRs along with the applicable US Government Principles. Since the PHSPolicy further requires that the provisions of the Guide apply, there are many other aspects of research that an IACUC should review, such as food and water deprivation, use of noxious stimuli, and physical restraint. The Guide provides useful guidance on these and other practices. Section C.2. Pro-tocol Review Criteria addresses many of the subjects described below in greater detail.
If the IACUC does not have the scientific and technical expertise to evaluate all aspects of a proposal it may bring in outside expert consultants to pro-vide information. Such consultants may not vote. In all cases, the onus should be on the investigator to justify and explain his or her proposed experiments to the satisfaction of the IACUC.
*This Guidebook generally uses the term “proposal” to describe the proposed use of animals. In some cases the term “protocol” is used for ease of readability. For the purposes of this Guidebook “proposal” is interchangeable with the commonly accepted use of the term “protocol”.
C.1. Table A. Regulatory Criteria Applicable to Protocol Review as Defined
each Principle refer to other Sections of this Guidebook.
PHS Policy on
Humane Care and Use
of Laboratory Animals
USDA AWR 9 CFR Part 2,
Principle I: The transportation, care and use of animals should be in accordance with the AWA (7 U.S.C.2131 et. seq.) and other applicable federal laws, guidelines, and policies*.
*For guidance throughout these Principles, the reader is referred to the Guide.
C.1.: ...the IACUC shall...determine that the proposed research projects are in accordance with this Policy...the IACUC shall con-firm that the research project will be conducted in accord-ance with the AWA insofar as it applies to the research project, and that the research project is consistent with the Guide unless acceptable justification for a departure is presented.
§2.31(d): ...The IACUC shall determine that the proposed activities are in accordance with this subchapter unless acceptable justification for a departure is presented in writing...
Principle II: Procedures involving animals should be designed and performed with due consideration of their scientific relevance to human or animal health, the advancement of knowledge, or the good of society.
§2.31(d)(1)(iii): The PI has provided written Assurance that the activities do not unnecessarily duplicate previous experiments.
Principle III: The animals selected for a procedure should be of an appropriate species and quality and the minimum number required to obtain valid results. Methods such as mathematical models, computer simulation, and in vitro biological systems should be considered.
(See C.2.a. Alternatives)
D.1.: Applications and proposals…that involve the care and use of animals shall contain the following: a.) Identification of the species and the approximate number of animals to be used;
b.) rationale for involving animals, and for the appro-priateness of the species and numbers of animals to be used…
§2.31(e): A proposal…must contain the following: (1) Identification of the species and approximate number of animals to be used; (2) A rationale for involving animals, and for the appropriateness of the species and numbers of animals to be used…