1. 1: Bioinstrumentation I



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1.1: Bioinstrumentation I

Thursday, October 2 10:30AM – 12:00PM

NCC 211/212


Chairs: Barry Peterson and Kyung Kang

10:30 1.1.1. Development of an Automated Anesthesia System for the Stabilization of Physiology in Rodents

K.M. HAWKINS AND R.D. SHONAT



Worcester Polytechnic Institute, Worcester, MA

10:45 1.1.2. Computational Fluid Dynamic Modelling of FLow in a Novel Paracorporeal Pumping Artificial Lung

W.J. FEDERSPIEL, I. ZINOVIK AND R.G. SVITEK



1University of Pittsburgh, Pittsburgh, PA

11:00 1.1.3. Measurement of Viscoelastic Properties of Tympanic Membrane (Eardrum)

R.Z. GAN1, B. FENG1, G. HUANG2 AND H. LU2



1University of Oklahoma, Norman, OK; 2Oklahoma State University, Stillwater, OK

11:15 1.1.4. Computer assisted coil design and bench testing for a totally implantable hearing system

T. CHENG AND R.Z. GAN



University of Oklahoma, Norman, OK

11:30 1.1.5. Optimal Design of Small-Diameter Silicone Chest Drain Devices

J. CHUNG AND J.K. LI



Rutgers, The State University of New Jersey, New Brunswick, NJ

2.1: Engineered Liver Constructs and Applications

Thursday, October 2 10:30AM – 12:00PM

NCC 205

Chairs: Dawn Applegate and Prabhas Moghe

10:30 2.1.1. An Explosion in Discovery/An Industry in Peril–Can Engineered Liver Assist a Conversion to Products?

D.R. APPLEGATE



Applegate & Associates, Inc., San Diego, CA

10:45 2.1.2. A Three Dimensional Perfused Liver Tissue Analog - A Tool for in vitro Drug Metabolism Studies

A. SIVARAMAN, T. IIDA, B. HOGAN, K.J. LEACH, M. KAAZEMPUR-MOFRAD, R. KAMM, S.R. TANNENBAUM AND L.G. GRIFFITH



Massachusetts Institute of Technology, Cambridge, MA

11:00 2.1.3. In vitro Thermal Stress Selectively Enhances Rat Hepatocyte Cytochrome P450 Activity

P. RAJAGOPALAN, F. BERTHIAUME, A.W. TILLES, M. TONER AND M.L. YARMUSH



Massachusetts General Hospital, Harvard Medical School, Shriners Burns Hospital, Boston, MA

11:15 2.1.4. Exploring Cell-Cell Interactions Using Expression Profiling and Dynamic Substrates

S. KHETANI1, G. SZULGIT2, W. YEO3, J. DEL RIO4, C. BARLOW4, M. MRKSICH3 AND S. BHATIA1



1UC - San Diego, La Jolla, CA; 2Hiram College, OH; 3University of Chicago, Chicago, IL; 4Merck Research Laboratories, La Jolla, CA

11:30 2.1.5. Direct Writing and Hepatocyte Co-Culture Support of Endothelial Tube-Like Network Formation In-Vitro

Y.K. NAHMIAS AND D. ODDE



University of Minnesota, Minneapolis, NM

11:45 2.1.6. Differentiation of Rat Liver Progenitor Cells in a 3D, Perfused Coculture with Mature Liver Cells

J.M. MORITZ, T. IIDA, S. LIU, J.L. SHERLEY AND L.G. GRIFFITH



Massachusetts Institute of Technology, Cambridge, MA

3.1: BME Education in Innovation, Design, & Entrepreneurship

Thursday, October 2 10:30AM – 12:00PM

NCC 204


Chairs: Paul King and Paul Yock

10:30 Overview of university programs in innovation, design, and entrepreneurship (Paul King)

10:45 A proposed national competition for BME student design (Phil Weilerstein, Jay Goldberg)

11:00 Re-inventing the industry advisory role for BME design & entrepreneurship classes (Jack Linehan)

11:15 3.1.1. Alliance for Industrial Internships: Members Perspective

C. TRIPLETT1, E.C. ECKSTEIN2 AND J.M. ALLEY3



1Biomedical Engineering Alliance for Industrial Internships, Chandler, AZ; 2University of Memphis, Memphis, TN; 3 Nashville, TN

11:30 A new web portal for BME design education (Paul Yock)

11:45 3.1.2. BME Education in Innovation, Design & Entrepreneurship

P.H. KING1, J. GOLDBERG2, P. WEILERSTIEN3, J.H. LINEHAN2 AND P.G. YOCK4



1Vanderbilt University, Nashville, TN; 2Marquette University, Milwaukee, WI; 3NCIIA; 4Stanford University, Stanford, CA

3.2: Student Chapter Development Workshop I

Thursday, October 2 10:30AM – 12:00PM

NCC 207


Chair: Kristina Ropella

10:30 3.2.1. Workshop I: BME Bytes

K. ROPELLA



Marquette University, Milwaukee, WI


4.1: Optical Spectroscopy for Diagnosis

Thursday, October 2 10:30AM – 12:00PM

RNH Davidson B

Chairs: Anita Mahadevan-Jansen and Shabbir Bambot

10:30 4.1.1. Integrating a Novel Tool for Burn Assessment into Clinical Practise

M.G. SOWA AND L. LEONARDI



National Research Council of Canada, Winnipeg, Manitoba, Canada

10:45 4.1.2. Comparison of Fluorescence and Diffuse Reflectance Spectroscopy for the Diagnosis of Breast Cancer

N. RAMANUJAM, C. ZHU, G. PALMER AND T. BRESLIN



University of Wisconsin-Madison, Madison, WI

11:00 4.1.3. Optical Imaging for in Situ Ovarian Diagnosis

U. UTZINGER1, M. BREWER1 AND R. DREZEK2



1University of Arizona, Tucson, AZ; 2Rice University, Houston, TX

11:15 4.1.4. Multimodal Spectroscopic Imaging of the Cervix for Triaging Patients to Colposcopy

K. CALLAHAN1, A. AGRAWAL2, S. BAMBOT3, D. MONGIN3, M. FAUPEL3, B. SCHULTZ3 AND F. XU3



1Spectrx Inc., Norcross, GA; 2Spectrx, Inc, PY, TN; 3Spectrx, PY, GA, PY

11:30 4.1.5. MEMS-based Endoscopic Fluorescence Confocal Microscope

D.L. DICKENSHEETS, Y. SHAO AND N.E. FERRADI



Montana State University, Bozman, MT

11:45 4.1.6. Diagnosis of Pre-Dysplastic Stages of Colon Carcinogenesis Using Light Scattering “Fingerprints”

V. BACKMAN1, Y.L. KIM1, Y. LIU1, K. CHEN1, R. WALI2, H. ROY2 AND M. GOLDBERG2



1Northwestern University, Evanston, IL; 2Evanston Northwestern Healthcare, Evanston, IL

5.1: Clinical Microdevices & NeuroMEMS

Thursday, October 2 10:30AM – 12:00PM

NCC 210


Chair: Sam Baldwin

10:30 5.1.1. The Potential of MEMS in the Management of Diabetes

D. LIEPMANN



University of California, Berkeley, Berkeley, CA

10:55 5.1.2. Integrated BioChips for the Detection of Cells and Microorganisms Using BioMEMS

R. BASHIR



Purdue University, West Lafayette, IN

11:20 5.1.3. Implantable BioMEMS for Drug Delivery

S. BALDWIN



MicroCHIPS, Inc., Bedford, MA

11:45 5.1.4. Microfluidic Delivery of Biomolecules in Neural Tissue

S.T. RETTERER1, K.L. SMITH2, C.S. BJORNSSON2, K.B. NEEVES1, A.J. SPENCE1, J.N. TURNER2, W. SHAIN2 AND M.S. ISAACSON3



1Cornell University, Ithaca, NY; 2New York State Department of Health, Wadsworth Center; 3University of California at Santa Cruz

6.1: Heart Valves

Thursday, October 2 10:30AM – 12:00PM

RNH Davidson A


Chair: Michael Sacks

10:30 6.1.1. Fluid Dynamic Analysis of an Anatomic Total Cavopulmonary Connection

D. DE ZÉLICOURT, K. PEKKAN AND A.P. YOGANATHAN



Georgia Institute of Technology, Atlanta, GA

10:45 6.1.2. Design and Evaluation of a Pulsatile Bioreactor for Biologically Active Heart Valves

D. HILDEBRAND1, J. WU1, J. MAYER2 AND M. SACKS1



1University of Pittsburgh, Pittsburgh, PA; 2Children's Hospital Boston

11:00 6.1.3. The Nature of the Disturbed Flow in Stenotic Blood Vessels at Moderate Reynolds Numbers.

V.L. RAYZ AND S.A. BERGER



UC-Berkeley, Berkeley, CA

11:15 6.1.4. Reversibility of Collagen Transformations during Dynamic Thermomechanical Studies

A. JAHANGIR AND J.M. LEE



Dalhousie University, Halifax, Nova Scotia, Canada

11:30 6.1.5. Polyurethane Heart Valve Calcification: Prevention With Bisphosphonate Diethylamino Derivatization

S. STACHELEK1, I. ALFERIEV1, A. FU2, T.L. SELLARO2, J.M. CONNOLLY1, R.W. BIANCO3, M. SACKS2 AND R. LEVY1



1Children's Hospital of Philadelphia, Philadelphia, PA; 2University of Pittsburgh, Pittsburgh, PA; 3University of Minnesota, Minneapolis, MN

11:45 6.1.6. Clinical Potential of Three-Dimensional Stress Echocardiography

J.W. HOLMES AND S. HOMMA



Columbia University, New York, NY

7.1: High Throughput Data Collection for Genome-Proteome & Cellular Modeling

Thursday, October 2 10:30AM – 12:00PM

NCC 208


Chair: David Galas

10:30 7.1.1. Blood phenotyping: Role of platelet activation in tissue factor-mediated thrombin production

K. LO1 AND S.L. DIAMOND1



1University of Pennsylvania, Philadelphia, PA

10:45 7.1.2. Proteomic Analysis of Cytokine Interactions in Determining Cellular Stress Responses

K. ROBERTS1, J. YOON2, K. LEE2, M. YARMUSH1 AND A. JAYARAMAN1



1Massachusetts General Hospital, Boston, MA; 2Tufts University, Medford, MA

11:00 7.1.3. Fidelity and sensitivity of microarray data following linear amplification from nanograms of RNA

A.G. PASSERINI, D.C. POLACEK, C. SHI, N.M. FRANCESCO, G. CHANG AND P.F. DAVIES



University of Pennsylvania, Philadelphia, PA

11:15 7.1.4. Biophysics of surface DNA hybridization: implications for DNA microarray assays

R. SINGH1, S.T. ANDREADIS2 AND J.M. NITSCHE1



1University at Buffalo, Buffalo, NY; 2University at Buffalo, Amherst, NY

9.1: Cellular Biomechanics I: Cytoskeleton

Thursday, October 2 10:30AM – 12:00PM

NCC 206


Chairs: Christopher Waters and Karen Haberstroh

10:30 9.1.1. Structural Mechanics in the Endothelial Cytoskeleton in Response to Extracellular Forces

B.P. HELMKE, N.A. VILLANI, R.E. MOTT AND C.K. CHOI



University of Virginia, Charlottesville, VA

10:45 9.1.2. Cyclic strain induces structural changes at the wound edge in airway epithelial cells

K. CHAPMAN1 AND C.M. WATERS2



1Northwestern University, Memphis, TN; 2University of Tennessee Health Science Center, Memphis, TN

11:00 9.1.3. Morphological and Cytoskeletal Modulations of Astrocytes on Substrates of Varying Rigidities

P.C. GEORGES AND P.A. JANMEY



University of Pennsylvania, Philadelphia, PA

11:15 9.1.4. Microfilament Rearrangement Following Exposure to a Clinically Relevant Pressure Stimulus

J.S. MARTIN, L.S. BROWN AND K.M. HABERSTROH



Purdue University, West Lafayette, IN

11:30 9.1.5. Intracellular actin and calcium contribute to stretch-induced increases in paracellular permeability

S.S. MARGULIES AND K.J. CAVANAUGH



University of Pennsylvania, Philadelphia, PA

11:45 9.1.6. Cell Biomechanics In Context

S.L. VOYTIK-HARBIN, A.M. PIZZO, B.A. ROEDER, B.Z. WAISNER, J.E. STURGIS, K. KOKINI AND J.P. ROBINSON



Purdue University, West Lafayette, IN

10.1: Vestibular Proscesses

Thursday, October 2 10:30AM – 12:00PM

NCC 209


Chairs: Dan Merfeld and Conrad Wall

10:30 10.1.1. Sensory Substitution for Balance Prostheses

C. WALL


Massachusetts Eye & Ear Infirmary, Boston, MA

11:00 10.1.2. Audio Biofeedback as a Source Of Balance Information for Vestibular Loss Subjects

M. DOZZA1, F. HORAK1, L. CHIARI2 AND R. PETERKA1



1Oregon Health & Science University, Beaverton, OR; 2University of Bologna, Italy

11:15 10.1.3. Effects of electrotactile vestibular substitution on bilateral vestibular dysfunction subjects.

Y. DANILOV, M. TYLER AND P. BACH-Y-RITA



University of Wisconsin-Madison, Madison, WI

11:30 10.1.4. Vestibular Implants: Overview and Preliminary Studies

D.M. MERFELD, R. LEWIS, C. HABURCAKOVA AND W. GONG



Harvard Medical School, Boston, MA

11:45 10.1.5. Development of a Biophysical Model for a Vestibular Prosthesis

J.T. RUBINSTEIN1 AND C.C. DELLA SANTINA2



1University of Iowa, Iowa City, IA; 2Johns Hopkins School of Medicine, Baltimore, MD

11.1: Orthopedic Tissue Engineering

Thursday, October 2 10:30AM – 12:00PM

RNH Ryman


Chairs: Karen Burg and Kirk Andriano

10:30 11.1.1. RANKL expression in ST2 bone marrow stromal cell regulated by titanium particle size

D. O'CONNOR1, H. KOH1, T. MURPHY2, A. TENG1, J. RUBIN2 AND K.L. SUNG1



1University of California, San Diego, La Jolla, CA; 2VAMC and Emory University, Atlanta, GA

10:45 11.1.2. Influence of Ph on Hydroxyapatite Solubility and Bone Cell Adhesion

T.J. WEBSTER AND J.L. SMITH



Purdue University, West Lafayette, IN

11:00 11.1.3. Fine-Particle Titanium Compacts Enhance Osteoblast and Fibroblast Cell Functions

J.U. EJIOFOR AND T.J. WEBSTER



Purdue University, West Lafayette, IN

11:15 11.1.4. Mechanical Stimulation of Periosteal Osteogenesis using an in vitro Organ Culture Model

I. YOUN, D.G. JONES AND J.F. SUH



Tulane University, New Orleans, LA

11:30 11.1.5. A Mechanical Loading Device for Three-Dimensional Natural and Engineered Tissues

K.K. WHITE, D.A. SHIMKO, E.A. NAUMAN AND K.C. DEE



Tulane University, New Orleans, LA

12.1: Respiratory Dynamics & Control

Thursday, October 2 10:30AM – 12:00PM

RNH Davidson C


Chairs: Bela Suki and Eugene Bruce

10:30 12.1.1. Power-laws in nature - where do they come from?

J.H. BATES



University of Vermont, Burlington, VT
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